Test Catalog

Test ID: DEXT    
Dermatopathology Consultation, Wet Tissue

Useful For Suggests clinical disorders or settings where the test may be helpful

Histologic diagnosis and differential diagnosis of cutaneous diseases

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

When this test is ordered, 1 of the 3 reflex tests will be performed and charged. Appropriate additional stains and other ancillary testing may be performed to determine a diagnosis. These stains and tests will be charged separately.


See Pathology Consultation Ordering Algorithm in Special Instructions.

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Dermatopathology involves histologic examination of skin biopsy and oral mucosal specimens.

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Diagnosis and description of microscopic findings

Interpretation Provides information to assist in interpretation of the test results

Histologic diagnosis is based primarily on interpretation of hematoxylin and eosin-stained sections. Special histochemical stains, such as alcian blue, Giemsa, or periodic acid-Schiff may be necessary in some cases.


Interpretation is based on evaluation of patterns including architectural and cytologic details, which are included in a microscopic description.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Specific diagnosis may require correlation with clinical information.

Clinical Reference Recommendations for in-depth reading of a clinical nature

1. Lever WF, Schaumburg-Lever G: Histopathology of the Skin. 7th ed. Philadelphia, JB Lippincott; 1990

2. Elder D, Elenitsas R, Rubin A, et al, eds: Atlas of Dermatopathology Synopsis and Atlas of Lever’s Histopathology of the Skin. 4th ed. Lippincott Williams and Wilkins; 2020

Special Instructions Library of PDFs including pertinent information and forms related to the test