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Test Catalog

Test ID: FBAC    
Bile Acids, Urine

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Diagnostic testing in pediatric and adult patients presenting with conditions of cholestatic liver disease, neurological disease, or fat-soluble vitamin malabsorption of unknown etiology. Urine FAB-MS analysis provides a rapid and cost-effective means of diagnosing the most common of the genetic defects in the metabolism of cholesterol to the primary bile acids. Mass spectrometry testing may be used to monitor the biochemical response to primary bile acid therapy and to help in decisions on dose adjustments, where compliance should lead to a reduction in levels of atypical bile acids.