Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
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Values are valid only on day of printing. |
Anti-cN-1A autoantibodies in idiopathic inflammatory myopathy (IIM) patients appear to be disease-specific for sporadic Inclusion Body Myositis (sIBM) and are rarely detected in other autoimmune conditions. Anti-cN-1A autoantibodies have a moderate sensitivity, but their high specificity for sIBM may be helpful in the diagnosis of this infrequent and difficult-to-diagnose myopathy. This assay can augment and accelerate the suspected diagnosis of sIBM using sera where muscle biopsy is delayed and/or unfeasible.
Reference Range: <20
Interpretation:
Negative: <20 units
Weak Positive: 20 - 39 units
Moderate Positive: 40 - 80 units
Strong Positive: >80 units