TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: BARBU    
Barbiturates Confirmation, Random, Urine

Useful For Suggests clinical disorders or settings where the test may be helpful

Detecting drug abuse involving barbiturates such as amobarbital, butalbital, pentobarbital, phenobarbital, and secobarbital

Clinical Information Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Barbiturates represent a class of drugs that were originally introduced as sleep inducers. Butalbital is also used to control severe headaches. Mephobarbital and phenobarbital are frequently used to control major motor (grand mal) seizures. These drugs are commonly abused as "downers" to induce sleep after an amphetamine- or cocaine-induced "high."

Reference Values Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Negative

 

Cutoff concentrations:

BUTALBITAL BY GC-MS

<100 ng/mL

 

AMOBARBITAL BY GC-MS

<100 ng/mL

 

PENTOBARBITAL BY GC-MS

<100 ng/mL

 

SECOBARBITAL BY GC-MS

<100 ng/mL

 

PHENOBARBITAL BY GC-MS

<100 ng/mL

Interpretation Provides information to assist in interpretation of the test results

The presence of a barbiturate in urine indicates use of one of these drugs.

 

Most of the barbiturates are fast acting; their presence indicates use within the past 3 days.

 

Phenobarbital, commonly used to control epilepsy, has a very long half-life. The presence of phenobarbital in urine indicates that the patient has used the drug sometime within the past 30 days.

Cautions Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements.

Clinical Reference Recommendations for in-depth reading of a clinical nature

1. Disposition of Toxic Drugs and Chemicals in Man. 10th edition. Edited by RC Baselt. Foster City, CA: Biomedical Publications, 2014

2. Langman LJ et al: Clinical Toxicology. In Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. Edited by N Rifai, AR Horvath, CT Wittwer. Sixth edition. Elsevier, 2018, pp 832-887