Direct measurement of Angiotensin II (Ang II) and Angiotensin (1-7) (Ang 1-7) in plasma Adjunct to plasma renin activity (PRA) and aldosterone measurements for the diagnosis of primary aldosteronism and renal-vascular hypertension. Adjunct, or alternative to, PRA for investigations of potential associations with outcomes of coronavirus infection. Drug studies as to renin-angiotensin system (RAS) manipulations that might be useful in treatment of cardiovascular diseases or corona virus infection. This test is not useful for establishing eligibility for a specific treatment as results must be interpreted in conjunction with the clinical status of the patient.