Web: | mayocliniclabs.com |
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Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Investigating idiopathic dysautonomic symptoms
Directing a focused search for cancer in patients with idiopathic dysautonomia
Investigating autonomic symptoms that appear in the course or wake of cancer therapy and are not explainable by recurrent cancer or metastasis (detection of autoantibodies in this profile helps differentiate autoimmune dysautonomia from the effects of chemotherapy)
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
ADEI | Dysautonomia, Interpretation, S | No | Yes |
ARBI | ACh Receptor (Muscle) Binding Ab | Yes | Yes |
GANG | AChR Ganglionic Neuronal Ab, S | No | Yes |
ANN1S | Anti-Neuronal Nuclear Ab, Type 1 | No | Yes |
DPPIS | DPPX Ab IFA, S | No | Yes |
GD65S | GAD65 Ab Assay, S | Yes | Yes |
VGKC | Neuronal (V-G) K+ Channel Ab, S | No | Yes |
CCN | N-Type Calcium Channel Ab | No | Yes |
CCPQ | P/Q-Type Calcium Channel Ab | No | Yes |
STR | Striational (Striated Muscle) Ab, S | Yes | Yes |
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
ARMO | ACh Receptor (Muscle) Modulating Ab | No | No |
AMPCS | AMPA-R Ab CBA, S | No | No |
AMPIS | AMPA-R Ab IF Titer Assay, S | No | No |
AMPHS | Amphiphysin Ab, S | No | No |
AMIBS | Amphiphysin Immunoblot, S | No | No |
AN1BS | ANNA-1 Immunoblot, S | No | No |
AN2BS | ANNA-2 Immunoblot, S | No | No |
CS2CS | CASPR2-IgG CBA, S | No | No |
CRMWS | CRMP-5-IgG Western Blot, S | No | No |
CRMS | CRMP-5-IgG, S | No | No |
DPPCS | DPPX Ab CBA, S | No | No |
DPPTS | DPPX Ab IFA Titer, S | No | No |
GABCS | GABA-B-R Ab CBA, S | No | No |
GABIS | GABA-B-R Ab IF Titer Assay, S | No | No |
LG1CS | LGI1-IgG CBA, S | No | No |
NMDCS | NMDA-R Ab CBA, S | No | No |
NMDIS | NMDA-R Ab IF Titer Assay, S | No | No |
PC1BS | PCA-1 Immunoblot, S | No | No |
PCTBS | PCA-Tr Immunoblot, S | No | No |
PCABP | Purkinje Cell Cytoplasmic Ab Type 1 | No | No |
PCAB2 | Purkinje Cell Cytoplasmic Ab Type 2 | No | No |
PCATR | Purkinje Cell Cytoplasmic Ab Type Tr | No | No |
If indirect immunofluorescence assay (IFA) patterns suggest CRMP-5-IgG, then CRMS and/or CRMP-5-IgG Western blot is performed at an additional charge.
If IFA patterns suggest amphiphysin antibody, then AMPHS and/or amphiphysin immunoblot is performed at an additional charge.
If IFA pattern suggests ANNA-1 antibody, then ANNA-1 and ANNA-2 immunoblot is performed at an additional charge.
If IFA pattern suggests PCA-1 antibody, then PCA-1 immunoblot is performed at an additional charge.
If IFA pattern suggests PCA-Tr antibody, then PCA-Tr immunoblot is performed at an additional charge.
If IFA pattern suggests Purkinje cell cytoplasmic antibody type 1, type 2, or type trace, then the appropriate antibody specific IFA is performed at an additional charge.
If IFA pattern suggests NMDA-receptor, then NMDA-receptor cell-binding assay (CBA) and NMDA-receptor titer are performed at an additional charge.
If IFA pattern suggests AMPA-receptor, then AMPA-receptor CBA and AMPA-receptor titer are performed at an additional charge.
If IFA pattern suggests GABA-B-receptor, then GABA-B-receptor CBA and GABA-B-receptor titer are performed at an additional charge.
If IFA pattern suggests DPPX antibody, then DPPX antibody CBA and DPPX titer are performed at an additional charge.
If acetylcholine (ACh) receptor binding antibody is greater than 0.02, then ACh receptor modulating antibodies and CRMP-5-IgG Western blot are performed at an additional charge.
If VGKC is above 0.00, LGI1-IgG CBA and CASPR2-IgG CBA are performed at an additional charge.
See Autoimmune Dysautonomia Evaluation Algorithm in Special Instructions.
AMPHS, AMPIS, ANN1S, CRMS, DPPIS, DPPTS, GABIS, NMDIS, PCAB2, PCABP, PCATR: Indirect Immunofluorescence (IFA)
AMPCS, CS2CS, DPPCS, GABCS, LG1CS, NMDCS: Cell Binding Assay (CBA)
ARMO: Live Cell Assay (LCA)
CRMWS: Western Blot (WB)
AMIBS, AN1BS, AN2BS, PC1BS, PCTBS: Immunoblot (IB)
ARBI, CCN, CCPQ, GANG, GD65S, VGKC: Radioimmunoassay (RIA)
STR: Enzyme-Linked Immunosorbent Assay (ELISA)