TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: PTHFN    
Parathyroid Hormone, Fine-Needle Aspiration Biopsy (FNAB)-Needle Wash

Method Description Describes how the test is performed and provides a method-specific reference

The saline needle-wash specimen is analyzed with the Roche Diagnostics PTH reagent assay performed on the Roche cobas 6000. The Roche cobas assay for determining intact parathyroid hormone (PTH) employs a sandwich test principle in which a biotinylated monoclonal antibody reacts with the N-terminal fragment (1-37) and a monoclonal antibody labeled with a ruthenium complex(a) reacts with the C-terminal fragment (38-84). Application of a voltage to the electrode then induces chemiluminescent emission, which is measured by a photomultiplier. The antibodies used in this assay are reactive with epitopes in the amino acid regions 26-32 and 37-42.(Package insert: Roche PTH reagent, Roche Diagnostics Corp, Indianapolis, IN July 2010)

 

For all samples with PTH concentrations above 40 pg/mL, a dilution series is performed. A linear dilution excludes hooking and most major interferences. Samples that contain PTH concentrations less than 40 pg/mL are spiked with exogenous PTH to identify possible interferences that may cause a false-low result.

PDF Report Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Saturday

Report Available The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

Same day/1 to 3 days

Specimen Retention Time Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

12 months

Performing Laboratory Location Indicates the location of the laboratory that performs the test

Rochester