TEST CATALOG ORDERING & RESULTS SPECIMEN HANDLING CUSTOMER SERVICE EDUCATION & INSIGHTS
Test Catalog

Test ID: ADIC    
Disseminated Intravascular Coagulation/Intravascular Coagulation and Fibrinolysis (DIC/ICF) Profile, Plasma

Testing Algorithm Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

Initial testing includes prothrombin time (PT), activated partial thromboplastin time (APTT), thrombin time (TT), fibrinogen, D-dimer, and disseminated intravascular coagulation/intravascular coagulation and fibrinolysis (DIC/ICF) profile interpretation.

If PT is >13.9 seconds, then PT mix will be performed at an additional charge.

If aPTT is > or =38 seconds, then aPTT mix and dilute Russell viper venom time (dRVVT) will be performed at an additional charge.

If dRVVT ratio is > or =1.20, then dRVVT mix and dRVVT confirmation will be performed at an additional charge.

If fibrinogen is <150 mg/dL, or clinically indicated, then PT-fibrinogen will be performed at an additional charge.

If D-dimer is >500 ng/mL fibrinogen equivalent units (FEU), then soluble fibrin monomer will be performed at an additional charge.

If aPTT mix is > or =38 seconds and TT is <35.0 seconds (no evidence of heparin), then platelet neutralization procedure will be performed at an additional charge.

If TT is > or =25.0 seconds, then reptilase time will be performed at an additional charge.

Specimen Type Describes the specimen type validated for testing

Plasma Na Cit

Ordering Guidance

This profile will not detect all bleeding disorders such as von Willebrand disease. For patients with amyloidosis and bleeding symptoms, obtaining a limited bleeding diathesis profile is suggested.

 

Multiple coagulation profile tests are available. See Coagulation Profile Comparison in Special Instructions for testing that is performed with each profile.

Shipping Instructions

Send the 5 aliquot tubes in the same shipping container.

Necessary Information

If priority specimen, mark request form, give reason, and request a call-back.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Patient Preparation: Patient should not be receiving Coumadin or heparin. If so, note on request.

Specimen Type: Platelet-poor plasma

Collection Container/Tube: Light-blue top (3.2% sodium citrate)

Submission Container/Tube: 5 Plastic vials

Specimen Volume: 5 mL in 5 plastic vials, each containing 1 mL

Collection Instructions:

1. For complete instructions, see Coagulation Guidelines for Specimen Handling and Processing in Special Instructions.

2. Centrifuge, transfer all plasma into a plastic vial, and centrifuge plasma again.

3. Aliquot plasma (1 mL per aliquot) into 5 separate plastic vials, leaving 0.25 mL in the bottom of centrifuged vial.

4. Freeze plasma immediately (no longer than 4 hours after collection) at -20 degrees C or, ideally < or =-40 degrees C.

Additional Information: Double-centrifuged specimen is critical for accurate results as platelet contamination may cause spurious results.

Special Instructions Library of PDFs including pertinent information and forms related to the test

Forms

1. Coagulation Patient Information (T675) in Special Instructions.

2. If not ordering electronically, complete, print, and send a Coagulation Test Request (T753) with the specimen.

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

5 mL in 5 plastic vials, each containing 1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
Plasma Na CitFrozen14 days