Test ID: RAVU    
Ravulizumab, Serum

Specimen Type Describes the specimen type validated for testing

Serum

Ordering Guidance

To screen test complement abnormalities in the alternative pathway, order RAVUM / Ravulizumab Complement Blockage Monitoring, Serum.

Specimen Required Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Patient Preparation: Natalizumab or eculizumab must be discontinued at least 4 weeks prior to testing for ravulizumab quantitation in serum.

Preferred: Red top

Acceptable: Serum gel

Specimen Volume: 2.5 mL

Collection Instructions:

1. Draw blood immediately before next scheduled dose.

2. Centrifuge within 2 hours of collection.

Forms

Specimen Minimum Volume Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

1.1 mL

Reject Due To Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus OK

Specimen Stability Information Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen TypeTemperatureTimeSpecial Container
SerumRefrigerated (preferred)28 days
 Ambient 28 days
 Frozen 28 days