Enzyme Linked Immunosorbent Assay (ELISA)
FRGAM
RF
Sjogren's Syndrome
Rheumatoid Arthritis
Systemic Lupus Erythematosus (SLE)
Autoimmune Hearing Loss (SNHL)
Serum
Container/Tube: Red-top tube
Acceptable: SST tube
Specimen Volume: 1.50 mL
Collection Instructions: Draw blood in a plain, red-top tube(s) or a serum-gel tube(s). Spin down and send 1.50 mL of serum refrigerated in a plastic vial.
0.50 mL
Hemolysis | Mild OK |
Lipemia | Mild OK |
Icterus | Mild OK |
Other | Whole blood unspun greater than 5 days old |
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 5 days | |
Frozen | 365 days | ||
Ambient | 5 days |
Rheumatoid Factor (RF) levels IgG:
Negative: <20 EU/mL
Borderline/Equivocal: 20-25 EU/mL
Positive: >25 EU/mL
Rheumatoid Factor (RF) levels IgA:
Negative: <20 EU/mL
Borderline/Equivocal: 20-25 EU/mL
Positive: >25 EU/mL
Rheumatoid Factor (RF) levels IgM:
Negative: <10 IU/mL
Borderline/Equivocal: 10-12.5 IU/mL
Positive: >12.5 IU/mL
The presence of abnormal levels of all three rheumatoid factor (RF) isotypes has a specificity of 99% for Rheumatoid Arthritis. IgA-RF alone can occur in Henoch Schoenlein purpura. RF in any isotype combination may be found in hepatitis C, Sjogren Syndrome, and other chronic infections.
Borderline/Equivocal RF results warrant redraw & retesting to confirm.
Once per week
This test has been developed and performance parameters have been validated by IMMCO Diagnostics, Inc. This test has not been approved by the U.S. Food and Drug Administration (FDA); however, US FDA approval is not required for clinical use. It is not intended that clinical diagnosis and patient management decisions be made using these results alone.
This test has been validated using serum samples. The manufacturer has not determined the efficacy of this when performed on CSF, plasma, joint or pleural fluid specimens. The performance characteristics of this test were determined by IMMCO Diagnostics Inc.
86431 x 3
Test Id | Test Order Name | Order LOINC Value |
---|---|---|
FRGAM | Rheumatoid Factor IgG, IgA, IgM | Not Provided |
Result Id | Test Result Name |
Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
|
---|---|---|
Z5623 | Rheumatoid Factor IgG | 33314-6 |
Z5624 | Rheumatoid Factor IgA | 33313-8 |
Z5625 | Rheumatoid Factor IgM | 11573-3 |