Web: | mayocliniclabs.com |
---|---|
Email: | mcl@mayo.edu |
Telephone: | 800-533-1710 |
International: | +1 855-379-3115 |
Values are valid only on day of printing. |
Confirmation of suspected clinical diagnosis of hereditary pancreatitis (HP) in patients with chronic pancreatitis
Identification of familial PRSSI mutation to allow for predictive and diagnostic testing in family members
Testing consists of full gene sequencing of the PRSS1 gene. Includes the following commonly observed mutations: R122H, N29I, and A16V.
-Full sequencing of the PRSS1 gene includes R122H, N29I, and A16V mutations
-Mutations in the PRSS1 gene are the most common cause of hereditary pancreatitis
-Useful for diagnostic confirmation of hereditary pancreatitis
Polymerase Chain Reaction (PCR) Amplification followed by DNA sequencing