Test Catalog

Test Id : HBEL0

Not Orderable

Hemoglobin Electrophoresis Summary Interpretation

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Overview

Test Catalog

Useful For
Suggests clinical disorders or settings where the test may be helpful

Incorporating and summarizing results into an overall evaluation with consultative interpretation on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test is an additional consultative interpretation that summarizes all testing as well as any pertinent clinical information available for review, and will be provided after all reflexed tests have been completed. If performed, subsequent molecular results will also be incorporated into the overall evaluation. One or more of the following molecular tests may be reflexed on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood:

-ATHAL / Alpha-Globin Gene Analysis, Varies

-WASQR / Alpha-Globin Gene Sequencing, Blood

-WBSQR / Beta-Globin Gene Sequencing, Blood

-WBDDR / Beta-Globin Cluster Locus Deletion/Duplication, Blood

-WGSQR / Gamma-Globin Full Gene Sequencing, Varies

 

This summary is in addition to interpretations that may be provided for each component.

Method Name
A short description of the method used to perform the test

Only orderable as a reflex. For more information see HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood.

 

Medical Interpretation.

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Hb Electrophoresis Summary Interp

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test is an additional consultative interpretation that summarizes all testing as well as any pertinent clinical information available for review, and will be provided after all reflexed tests have been completed. If performed, subsequent molecular results will also be incorporated into the overall evaluation. One or more of the following molecular tests may be reflexed on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood:

-ATHAL / Alpha-Globin Gene Analysis, Varies

-WASQR / Alpha-Globin Gene Sequencing, Blood

-WBSQR / Beta-Globin Gene Sequencing, Blood

-WBDDR / Beta-Globin Cluster Locus Deletion/Duplication, Blood

-WGSQR / Gamma-Globin Full Gene Sequencing, Varies

 

This summary is in addition to interpretations that may be provided for each component.

Specimen Type
Describes the specimen type validated for testing

Whole Blood EDTA

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Whole Blood EDTA Refrigerated

Useful For
Suggests clinical disorders or settings where the test may be helpful

Incorporating and summarizing results into an overall evaluation with consultative interpretation on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

This test is an additional consultative interpretation that summarizes all testing as well as any pertinent clinical information available for review, and will be provided after all reflexed tests have been completed. If performed, subsequent molecular results will also be incorporated into the overall evaluation. One or more of the following molecular tests may be reflexed on the HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood:

-ATHAL / Alpha-Globin Gene Analysis, Varies

-WASQR / Alpha-Globin Gene Sequencing, Blood

-WBSQR / Beta-Globin Gene Sequencing, Blood

-WBDDR / Beta-Globin Cluster Locus Deletion/Duplication, Blood

-WGSQR / Gamma-Globin Full Gene Sequencing, Varies

 

This summary is in addition to interpretations that may be provided for each component.

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

The evaluation of hemoglobin disorders can be very complex. This can involve abnormalities in the alpha, beta, delta, or gamma chains. Molecular testing is performed to fully evaluate complex situations. A summary interpretation that incorporates all of the testing performed is beneficial to the ordering physician.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Only orderable as a reflex. For more information see HBEL1 / Hemoglobin Electrophoresis Evaluation, Blood.

 

An interpretive report will be provided.

Interpretation
Provides information to assist in interpretation of the test results

An interpretive report will be provided that summarizes all testing as well as any pertinent clinical information.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

No significant cautionary statements.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. Hoyer JD, Hoffman DR. The thalassemia and hemoglobinopathy syndromes. In: McClatchey KD, ed. Clinical Laboratory Medicine. 2nd ed. Lippincott Williams and Wilkins; 2002:866-895

2. Harteveld CL, Higgs DR. Alpha-thalassemia. Orphanet J Rare Dis. 2010;5:13

3. Thein SL. The molecular basis of beta-thalassemia. Cold Spring Harb Perspect Med. 2013;3(5):a011700

4. Crowley MA, Mollan TL, Abdulmalik OY, et al. A hemoglobin variant associated with neonatal cyanosis and anemia. N Engl J Med. 2011;364(19):1837-1843

5. Kipp BR, Roellinger SE, Lundquist PA, Highsmith WE, Dawson DB. Development and clinical implementation of a combination deletion PCR and multiplex ligation-dependent probe amplification assay for detecting deletions involving the human alpha-globin gene cluster. J Mol Diagn. 2011;13(5):549-557. doi:10.1016/j.jmoldx.2011.04.001

6. Hein MS, Oliveira JL, Swanson KC, Lundquist PA. Large deletions involving the beta globin gene complex: genotype-phenotype correlation of 119 cases. Blood. 2015;126(23):3374. doi:10.1182/blood.V126.23.3374.3374

Method Description
Describes how the test is performed and provides a method-specific reference

A hematopathologist evaluates all of the testing performed and a summary interpretive report is added.

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

2 to 25 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their account representative. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

Not Applicable

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

83020-26

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
HBEL0 Hb Electrophoresis Summary Interp In Process
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
608091 Hb Electrophoresis Summary Interp 13514-5
608117 Reviewed By 18771-6

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | PHP Pdf | CMS Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports