Test Catalog

Test Id : CTFNA

Cytology Fine-Needle Aspiration, Varies

Useful For
Suggests clinical disorders or settings where the test may be helpful

Detection of malignancy

 

Detection of certain inflammatory conditions

Reflex Tests
Lists tests that may or may not be performed, at an additional charge, depending on the result and interpretation of the initial tests.

Test Id Reporting Name Available Separately Always Performed
APTGR Thyroglobulin Reflex, FNA Wash, Ts No No

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If an additional specimen is submitted along with the slides, then a cell block will be made at an additional charge.

 

Includes testing from virtually any body site that can be aspirated with a fine-needle (22-gauge or smaller).

Method Name
A short description of the method used to perform the test

Light Microscopy

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

Yes

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

Cytology Fine Needle Aspiration

Aliases
Lists additional common names for a test, as an aid in searching

Fine Needle Aspiration, Cytology

FNA (Fine Needle Aspiration)

FNAM

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If an additional specimen is submitted along with the slides, then a cell block will be made at an additional charge.

 

Includes testing from virtually any body site that can be aspirated with a fine-needle (22-gauge or smaller).

Specimen Type
Describes the specimen type validated for testing

Varies

Ordering Guidance

If a consultation is desired, order PATHC / Pathology Consultation.

Necessary Information

1. An acceptable cytology request form must accompany specimen containers and include the following: Patient's name, medical record number, date of birth, sex, source (exact location and procedure used), date specimen was taken, name of ordering physician and pager number.

2. Submit any pertinent history or clinical information.

ORDER QUESTIONS AND ANSWERS

Question ID Description Answers
CY067 Collection Procedure
CY054 Source
CY055 Clinical History
CY056 Fixative

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Specimen Type: Slide

Container/Tube: Plastic slide container

Specimen Volume: Smear

Collection Instructions:

1. Smears should be immediately fixed in 95% ethanol or sprayed with commercially available fixative. Smears that have been air-dried or Diff-Quik stained may also be accepted.

2. Label containers with a minimum of 2 unique identifiers (eg, patient name and medical record number or date of birth), specimen source, and date of collection. Label each glass slide in pencil with a minimum of 2 unique identifiers. If multiple slides are submitted, each slide must have proper identification.

 

Specimen Type: Fluid

Container/Tube: 60-mL (2 oz) jar with screw cap, 50-mL disposable centrifuge tube with screw cap, or 15-mL test tube with screw cap

Specimen Volume: Any amount

Collection Instructions:

1. Preferred method is no fixative added to fluid prior to processing and the specimen must be received and processed by the Cytology Laboratory within 1 hour of collection.

2. If not possible to submit within 1 hour, specimen should be refrigerated no longer than 62 hours. Additional acceptable fixatives are specimens with equal volume of 50%, 70%, 80%, or 95% ethanol, PreservCyt solution, CytoRich Red, or CytoLyt.

3. Label containers with a minimum of 2 unique identifiers (eg, patient name and medical record number or date of birth), specimen source, and date of collection.

 

Specimen Type: Tissue

Container/Tube: 50-mL disposable centrifuge tube with screw cap or 60-mL (2 oz) jar with screw cap containing 10% neutral-buffered formalin

Specimen Volume: Any amount

Collection Instructions:

1. Tissue fragments must be submitted in 10% neutral-buffered formalin.

2. Label containers with a minimum of 2 unique identifiers (eg, patient name and medical record number or date of birth), specimen source, and date of collection.

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

No specimen should be rejected.

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
Varies Ambient (preferred)
Refrigerated

Useful For
Suggests clinical disorders or settings where the test may be helpful

Detection of malignancy

 

Detection of certain inflammatory conditions

Testing Algorithm
Delineates situations when tests are added to the initial order. This includes reflex and additional tests.

If an additional specimen is submitted along with the slides, then a cell block will be made at an additional charge.

 

Includes testing from virtually any body site that can be aspirated with a fine-needle (22-gauge or smaller).

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Aspiration cytology from a variety of organ sites is useful in the determination of pathologic states, particularly neoplasms. Commonly examined sites include lung, liver, lymph nodes, pancreas, kidney, thyroid, retroperitoneum, breast, salivary glands, and soft tissue. In many cases, an open biopsy is no longer required to make a diagnosis.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Negative for malignant cells

Interpretation
Provides information to assist in interpretation of the test results

Aspiration therapy is highly specific with rare false-positives. A positive diagnosis should be definitive for malignancy.

 

Precise cell typing is variably possible depending on circumstances.

Cautions
Discusses conditions that may cause diagnostic confusion, including improper specimen collection and handling, inappropriate test selection, and interfering substances

Nondiagnostic results are issued when material is inadequate for a diagnostic impression.

 

A negative result must not be taken as definitive in the face of strong clinical suspicion. If the diagnosis is less than definitive (ie, suspicious), a follow-up biopsy may be recommended.

 

This test is not useful for most inflammatory conditions such as hepatitis, glomerulonephritis, etc. However, it may be helpful in obtaining material for culture and in identifying positive organisms in infectious diseases.

 

Slides must be fixed promptly after smearing to ensure adequate evaluation.

Clinical Reference
Recommendations for in-depth reading of a clinical nature

Mody DR, Thrall MJ, Krishnamurthy S, eds. Diagnostic Pathology: Cytopathology, 2nd ed. Elsevier, 2019

Method Description
Describes how the test is performed and provides a method-specific reference

Slides are stained by a modified Papanicolaou method and examined microscopically. DiffQuik stains may be used on air-dried specimens. On rare occasions, immunostains may be used secondarily as appropriate.(Unpublished Mayo method)

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

2 to 5 days

Specimen Retention Time
Outlines the length of time after testing that a specimen is kept in the laboratory before it is discarded

Indefinite

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Rochester

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

  • Authorized users can sign in to Test Prices for detailed fee information.
  • Clients without access to Test Prices can contact Customer Service 24 hours a day, seven days a week.
  • Prospective clients should contact their account representative. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

88173

88305-CBKPC (if appropriate)

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
CTFNA Cytology Fine Needle Aspiration 33718-8
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
71690 Interpretation 59465-5
71691 Participated in the Interpretation No LOINC Needed
71689 Report electronically signed by 19139-5
71274 Addendum 35265-8
71275 Gross Description 22634-0
71644 Adequacy Evaluation 11552-7
CY067 Collection Procedure 33724-6
CY054 Source 22633-2
CY055 Clinical History 22636-5
CY056 Fixative 8100-0
71566 Disclaimer 62364-5
71812 Case Number 80398-1

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | PHP Pdf | CMS Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports