Test Catalog

Test Id : FVIP2

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Vasoactive Intestinal Polypeptide (VIP), Plasma

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Overview

Test Catalog

Method Name
A short description of the method used to perform the test

Vasoactive Intestinal Polypeptide is measured by a direct ELISA.

NY State Available
Indicates the status of NY State approval and if the test is orderable for NY State clients.

No

Reporting Name
Lists a shorter or abbreviated version of the Published Name for a test

VIP, Plasma

Aliases
Lists additional common names for a test, as an aid in searching

VIP

Specimen Type
Describes the specimen type validated for testing

EDTA Plasma

Specimen Required
Defines the optimal specimen required to perform the test and the preferred volume to complete testing

Patient Preparation: The patient should fast for 10 to 12 hours prior to collection of specimen. Patient should not be on any antacid medications or medications that affect intestinal motility for at least 48 hours prior to collection.

Specimen Type: Plasma

Collection Container/Tube: Lavender top (EDTA)

Submission Container/Tube: Preservative-free plastic vial

Specimen Volume: 1 mL

Collection Instructions: Draw blood in an EDTA (lavender top) tube(s). Spin down and freeze immediately. Send 1 mL of plasma frozen in a preservative-free plastic vial.

Specimen Minimum Volume
Defines the amount of sample necessary to provide a clinically relevant result as determined by the Testing Laboratory

0.5 mL

Reject Due To
Identifies specimen types and conditions that may cause the specimen to be rejected

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Specimen Stability Information
Provides a description of the temperatures required to transport a specimen to the performing laboratory, alternate acceptable temperatures are also included

Specimen Type Temperature Time Special Container
EDTA Plasma Frozen 180 days

Clinical Information
Discusses physiology, pathophysiology, and general clinical aspects, as they relate to a laboratory test

Vasoactive Intestinal Polypeptide (VIP) is a 28 amino acid multifunctional peptide that is involved in gastrointestinal, vasodilator, and neuroendocrine functions.  VIP is derived from larger pro-molecules that often exhibit the same or greater immunogenicity than the native VIP.  It is structurally related to PHIM, Glucagon, Secretin, Gastric Inhibitory Polypeptide, Corticotropin Releasing Factor and Growth Hormone-Releasing Hormone.  VIP stimulates pituitary release of Prolactin, Growth Hormone and ACTH; stimulates Luteinizing Hormone-Releasing Hormone, Serotonin, gastric Somatostatin, Steroids and Renin.  VIP inhibits the release of Gastrin, hypothalamic Somatostatin, and Histamine.  VIP release is stimulated by cholinergic agonists, Atropine, Serotonin, Prostaglandins E1 and D2, and Nerve Growth Factor.  VIP actions are inhibited by Corticosteroids, Dopamine and opiate agonists.  Elevated levels of VIP are found in patients with VIPomas, hepatic cirrhosis, and the Verner-Morrison’s (Watery Diarrhea) Syndrome.  Decreased levels are found in cystic fibrosis.

Reference Values
Describes reference intervals and additional information for interpretation of test results. May include intervals based on age and sex when appropriate. Intervals are Mayo-derived, unless otherwise designated. If an interpretive report is provided, the reference value field will state this.

Up to 36 pg/mL

(mean 14)

Clinical Reference
Recommendations for in-depth reading of a clinical nature

1. MS O’Dorisio, CL Wood, and TM O’Dorisio.  Vasoactive Intestinal Peptide and Neuropeptide Modulation of the Immune Response.  Journal of Immunology 135: 792, 1985.

 

2. S Ollerenshaw, D Jarvis, A Woolcock.  Absence of Immunoreactive Vasoactive Intestinal Polypeptide in Tissue from the Lungs of Patients with Asthma.  New England Journal of Medicine 320:  1244, 1989

PDF Report
Indicates whether the report includes an additional document with charts, images or other enriched information

No

Day(s) Performed
Outlines the days the test is performed. This field reflects the day that the sample must be in the testing laboratory to begin the testing process and includes any specimen preparation and processing time before the test is performed. Some tests are listed as continuously performed, which means that assays are performed multiple times during the day.

Monday through Friday

Report Available
The interval of time (receipt of sample at Mayo Clinic Laboratories to results available) taking into account standard setup days and weekends. The first day is the time that it typically takes for a result to be available. The last day is the time it might take, accounting for any necessary repeated testing.

5 to 9 days

Performing Laboratory Location
Indicates the location of the laboratory that performs the test

Inter Science Institute

Fees
Several factors determine the fee charged to perform a test. Contact your U.S. or International Regional Manager for information about establishing a fee schedule or to learn more about resources to optimize test selection.

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  • Prospective clients should contact their account representative. For assistance, contact Customer Service.

Test Classification
Provides information regarding the medical device classification for laboratory test kits and reagents. Tests may be classified as cleared or approved by the US Food and Drug Administration (FDA) and used per manufacturer instructions, or as products that do not undergo full FDA review and approval, and are then labeled as an Analyte Specific Reagent (ASR) product.

This test was developed and its performance characteristics determined by Inter Science Institute. It has not been cleared or approved by the US Food and Drug Administration. The FDA had determined that such clearance or approval is not necessary.

CPT Code Information
Provides guidance in determining the appropriate Current Procedural Terminology (CPT) code(s) information for each test or profile. The listed CPT codes reflect Mayo Clinic Laboratories interpretation of CPT coding requirements. It is the responsibility of each laboratory to determine correct CPT codes to use for billing.

CPT codes are provided by the performing laboratory.

84586

LOINC® Information
Provides guidance in determining the Logical Observation Identifiers Names and Codes (LOINC) values for the order and results codes of this test. LOINC values are provided by the performing laboratory.

Test Id Test Order Name Order LOINC Value
FVIP2 VIP, Plasma 3125-2
Result Id Test Result Name Result LOINC Value
Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure.
FVIP2 VIP, Plasma 3125-2

Test Setup Resources

Setup Files
Test setup information contains test file definition details to support order and result interfacing between Mayo Clinic Laboratories and your Laboratory Information System.

Excel | PHP Pdf | CMS Pdf

Sample Reports
Normal and Abnormal sample reports are provided as references for report appearance.

Normal Reports | Abnormal Reports

SI Sample Reports
International System (SI) of Unit reports are provided for a limited number of tests. These reports are intended for international account use and are only available through MayoLINK accounts that have been defined to receive them.

SI Normal Reports | SI Abnormal Reports